Crystalization

Crystalization

Many thanks to our client who suggested we write this post after asking a question about crystallisation. We hope the information is helpful!

That happens very infrequently, but you may occasionally see irregularities in the oil in vials, or there may even be a hard layer floating on top.

In this situation, testosterone, the active component, is crystallising. Testosterone "long" esters like cypionate and undecanoate are prone to crystallisation.

It is crucial to add ingredients that promote solubility and have sterile properties to the mix while making the product, in addition to the carrier oil. The active ingredient is then completely dissolved as a result of the high temperature.

This makes it obvious that reducing the temperature can cause the product to crystallise. It's uncommon, but it's conceivable with our products. harmaceutical formulations commonly experience crystallisation. Retabolil, Testosterone Cypionate, and Undecanoate have direct recommendations in the medical literature that, in the event of crystallisation, the ampoule should be heated until the inhomogeneities vanish.

The product is extremely vulnerable to crystallisation when exposed to temperatures below those listed on the label (between 20°C and 25°C, or 68°F and 77°F), due to the high concentration of active components. The USPI and the product vial label both contain instructions that expressly address this product attribute

Hence, crystallisation has been demonstrated by an official investigation and confirmed by a trained commission to have no effect whatsoever on the product's quality. It's crucial to understand!

Please keep in mind that it could not be desirable if there is no crystallisation at any temperature. Aggressive solvents, which are frequently used in low-quality products, prevent crystallisation even in cold temperatures; however, this makes the liquid more irritating to human tissues, making systemic inflammation and pimples highly likely; for this reason, we, as legitimate manufacturers, avoid it.

So what do you need to do?

In this case, shake the vial occasionally while putting it in a pot of boiling water to dissolve the crystals.

Use your microwave to warm up some water. Once the crystals are gone, place the vial halfway in the hot water, wait 30 seconds, shake the vial slightly, and repeat with hotter water. If adding water didn't help the crystals dissolve:

You can place the vial on a skillet and gradually heat it until they are all totally dissolved. Practice has shown that it may take up to 10-15 minutes.

Important: after this, the oil must be cooled to a temperature of 38 degrees before injecting, even if heat-resistant medical glass is used and the chance of the vial bursting due to temperature fluctuations is quite minimal.