What is IGF-1 LR3?

IGF-1 LR3 (Long R3 Insulin-Like Growth Factor-1) is a synthetic, extended-action version of human IGF-1 — one of the most potent anabolic peptides. It promotes muscle cell growth, fat reduction, vascularity, recovery, and hyperplasia (formation of new muscle fibers).

The LR3 modification extends IGF-1’s half-life from ~20 minutes to 20–30 hours, making it dramatically stronger and longer-acting. Because of this, IGF-1 LR3 is commonly used by athletes and bodybuilders during growth phases or recomposition cycles.

Main Effects of IGF-1 LR3

???? Accelerated muscle growth

Stimulates muscle cell proliferation and increases protein synthesis, helping build lean mass quickly.

???? Muscle fiber hyperplasia

Unlike steroids that only enlarge existing fibers, IGF-1 LR3 can create new muscle cells — effects that persist even after stopping the peptide.

⚡ Faster recovery & reduced inflammation

Promotes tissue healing, reduces muscle soreness, and speeds up recovery after heavy training.

???? Fat loss & improved body composition

Enhances nutrient partitioning and increases the use of fat for fuel.

???? Better pumps and vascularity

Improves blood flow by increasing nitric oxide levels and supporting nutrient delivery.

???? Cognitive benefits

Some users report sharper focus, improved mood, and faster neural recovery.

How to Take IGF-1 LR3

Typical Dosage

• 20–40 mcg per day, depending on goal and experience

• Max recommended daily dose: 50–60 mcg

When to take?

• Best taken once daily, post-workout or first thing in the morning

• Training days: post-workout enhances absorption into active muscle tissue

• Non-training days: take in the morning

Where to inject?

• Subcutaneous (abdomen, thigh)

• Intramuscular (into trained muscle for local effect)

Cycle length

• 4–6 weeks recommended

• 8 weeks maximum

• Follow with at least a 4-week break

Reconstitution

IGF-1 LR3 comes as 1 mg lyophilized powder.

To prepare for injection:

• Add 1–2 mL bacteriostatic water to the vial

• Inject slowly, allowing water to run down the side (do not shake)

• Rotate vial gently until dissolved

Precautions

• Avoid using with insulin unless guided by a professional

• Use caution if prone to low blood sugar

• Not recommended for individuals with active cancer or tumors (IGF can stimulate cell growth)

• Monitor appetite, blood sugar, and recovery response

• Do not combine with GH secretagogues on first cycle unless experienced

Possible Side Effects

Most common:

• Fatigue

• Mild hypoglycemia

• Headache

• Increased hunger

• Temporary redness at injection site

Less common:

• Numbness/tingling in hands

• Water retention

• Joint pain

Rare but serious:

• Hypoglycemic episodes

• Unwanted tissue growth when overdosed

How to Store

• Store the unmixed vial in the refrigerator at 2–8°C

• Keep protected from light

• Do NOT freeze

• After reconstitution, store refrigerated and use within 30 days

How IGF-1 LR3 Works

1. Cellular growth & protein synthesis

IGF-1 binds to IGF-1 receptors in muscle tissue, triggering:

• cell growth

• protein synthesis

• nutrient uptake

• recovery acceleration

2. Muscle fiber hyperplasia

One of the rare compounds capable of creating new muscle fibers — a benefit that may remain even after the cycle.

3. Enhanced glucose uptake

IGF-1 mimics insulin, pushing nutrients directly into muscle cells and improving nutrient partitioning.

4. Fat oxidation

Improves the body’s ability to use fat for energy while preserving muscle mass.

5. Synergy with training

IGF-1 is highly absorbed by trained muscle, making timing (post-workout) especially effective.

FAQ

How long does it take to see results?

Most users notice improved pumps and recovery in 3–5 days, with physique changes becoming visible in 2–3 weeks.

Is IGF-1 LR3 better than HGH?

They work differently:

• HGH: long-term fat loss, skin benefits, recovery

• IGF-1 LR3: direct muscle growth, hyperplasia, fast performance boost
  Stacked together, they synergize extremely well.

Can I take IGF-1 LR3 every day?

Yes — daily dosing is the standard protocol.

Should I inject into the muscle I trained?

This may increase local absorption but is not required. Both IM and subcutaneous are effective.

Is IGF-1 LR3 safe for beginners?

It is a powerful peptide — beginners should start with 20 mcg/day.